Patents

Blizzard, T.A., Disney, M.; “Dimer Compounds, And Use In Binding Toxic Repeats Of RNA” US 20200207744 (A1)

Disney, M.; Blizzard, T.A., Rzuczek, S.; Ndungu, J.; Vacca, J.; Jennings, A.; Pushechnikov, A. “Bis-Benzimidazole Compounds And Methods Of Using The Same” US 2019152924 (A1)

Scott, J.D.; Blizzard, T.A., Walsh, S.P.; Cumming, J.N “C5-C6-Carbocyclic Fused Iminothiadiazine Dioxides As Bace Inhibitors, Compositions, And Their Use” US 10,329,291 (2019)

Berger, R., Blizzard, T.A., Campbell, B.T., Chen, H.Y., Debenham, J.S., Dewnani, S.V., Dubois, B., Gude, C., Guo, Z.Z., Harper, B., Hu, Z., Lin, S., Liu, P., Wang, M., Ujjainwalla, F., Xu, J., Xu, L., Zhang, R., “Isoquinoline Derivatives as MGAT2 Inhibitors” US 10,065,945

Biftu, T., Biju, P., Blizzard, T.A., Chen, Z., Clements, M.J., Cui, M., Frie, J.L., Hagmann, W., Hu, B., Josien, H., Nair, A.G., Plummer, C.W., Zhu, C. “Antidiabetic Tricyclic Compounds” US 10,000,454 (2018).

Hagmann, W., Li, B.; Szewczyk, J.W.; Wang, B.; Parker, D.; Blizzard, T.; Josien, H.; Purakkattle, B.; Chobanian, H.; Gude, C.; Nargund, R.; Pio, B.; Dang, Q.; Lin, L.S.; Hu, B.; Cui, M.; Chen, Z.; Dai, M.; Zhang, Z.; Lv, Y.; Tian, L. “Antidiabetic substituted heteroaryl compounds” US 9,834,563 (2017).

Scott, J.D., Cumming, J.N., Blizzard, T., Ellis, M., “C-6 spirocarbocyclic iminothiadiazine dioxides as BACE inhibitors, compositions, and their use” US 9,802,928 (2017)

Hagmann; W.K., Nargund; R.P., Blizzard; T.A., Josien; H., Biju, P., Plummer, C., Dang, Q., Li, B., Li, D., Lin, L.S., Cui, M., Hu, B., Hao, J., Chen., Z. “Antidiabetic Tricyclic Compounds” US 9,527,875 (2016).

Mandal, M., Blizzard, T.A., Chen, H., Chobanian, H., Guo, Y., Pio, B., Wu, Z., Biftu, T., Greenlee, W., Zhu, J.Z. “Preparation and Use of Bicyclic Himbacine Derivatives as PAR-1 Receptor Antagonists” US 9,340,530 (2016)

Walsh, S., Pasternak, A., De Jesus, R., Tang, H., Pio, B., Shahripour, A., Belyk,K., Chobanian, H., Guo, Y., Frie, J., Shi, Z., Chen, H., Blizzard, T., Cato, B. “Inhibitors of the Renal Outer Medullary Potassium Channel” US 9,139,585 (2015).

Blizzard, T.A., Biftu, T. “Thrombin Inhibitors” US 9,133,147 (2015).

Pasternak, A., Blizzard, T., Chobanian, H., De Jesus, R., Ding, F., Dong, S., Gude, C., Kim, D., Tang, H., Walsh, S., Pio, B., Jiang, J. “Inhibitors of the Renal Outer Medullary Potassium Channel” US 9,062,070 (2015).

Blizzard, T.A., Chen, H.Y., Gude, C., Hermes, J.D., Imbriglio, J.E., Kim, S., Wu, J.Y., Ha, S., Mortko, C.J., Mangion, I., Rivera, N., Ruck, RT…, Shevlin, M.  “Beta-Lactamase Inhibitors.”  US 8,487,093 (2011).

Blizzard, Timothy A., Chen, Helen Y., Wu, Jane Y., Kim, Seongkon; Ha, Sookhee; Mortko, Christopher J., Variankaval, N., Chiu, A.  “Novel Inhibitors Of Beta-Lactamase.”  US 2010/0009957 A1 (2010).

Blizzard, T.A., DiNinno, F.P., Morgan, J.D. “Estrogen Receptor Modulators.”  U.S. 7,138,426 (2006).

Blizzard, T.A., Hammond, M.L., Morgan, J.D., Mosley, R.T.  “Estrogen Receptor Modulators.”  U.S. 6,838,584 (2005).

Blizzard, T.A., Dykstra, K.D., and Ratcliffe, R.W.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.”  U.S. 6,346,526 (2002).

Blizzard, T.A., Ratcliffe, R.W., Waddell, S.T., and Morgan II, J.D.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.”  U.S. 6,346,525 (2002).

Blizzard, T.A., Wilkening, R.R., and Ratcliffe, R.W.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.”  U.S. 6,294,528 (2001).

Blizzard, T.A., Wilkening, R.R., and Ratcliffe, R.W.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.”  U.S. 6,291,448 (2001).

Blizzard, T.A., and Ratcliffe, R.W.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.”  U.S. 6,265,395  (2001).

Blizzard, T.A., Ratcliffe, R.W., Morgan, J.D., and Wilkening, R.R.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.”  U.S. 6,251,890 (2001).

Ratcliffe, R.W., and Blizzard, T.A. “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.” U.S. 6,008,212 (1999).

Wilkening, R.R., Ratcliffe, R.W., and Blizzard, T.A.  “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.” U.S. 5,756,725 (1998).

Blizzard, T.A., Ratcliffe, R.W., Waddell, S.T., Szumiloski, S.P., Wilkening, R.R., and Wildonger, K.J. “Carbapenem Antibacterial Compounds, Compositions Containing Such Compounds And Methods Of Treatment.” U.S. 5,496,816 (1996).

Waddell, S.T. and Blizzard, T.A. “Process of Producing 8a- and 9a- Azalide Antibiotics.”  U.S. 5,332,807 (1994).

Waddell, S.T. and Blizzard, T.A. “Methods of Elaborating Erythromycin Fragments into Amine-Containing Fragments of Azalide Antibiotics.” U.S. 5,210,235 (1993).

Blizzard, T.A. and Margiatto, G.  “Avermectin Derivatives With A Spacer Inserted Between The Disaccharide And The Aglycone Useful As Antiparasitic Agents.”  U.S. 5,114,930  (1992).

Blizzard, T.A.  “Avermectin Ketal Derivatives Useful as Antiparasitic Agents.” U.S. 5,077,308 (1991).

Blizzard, T.A. and Mrozik, H.  “13-epi-Avermectin Derivatives Useful as Antiparasitic Agents.”  U.S. 5,055,454 (1991).

Blizzard, T.A., Mrozik, H., Marino, G., and Sinclair, P.J.  “Synthetic Derivatives of Paraherquamide.”  U.S. 4,978,656 (1990).

Blizzard, T.A. and Mrozik, H. “Synthetic Marcfortine Derivatives Useful as Antiparasitic Agents.”  U.S. 4,923,867 (1990).