presentations

Blizzard, T.A. “Overcoming Bacterial Resistance To Beta-Lactam Antibiotics.  A Tale Of Two Drug Discovery Programs” University Of Pennsylvania, Philadelphia, PA, February 2013 and February 2012, (invited guest lecture for medicinal chemistry course.

Blizzard, T.A., Singh, S., Patil, B., Chidurala, N., Komanduri, V., Debnath, S., Belyakov, S., Struck, A., Kurtz, M., Wiltsie, J., Shen, XA., Sonatore, L., Arocho, M., Lewis, D., Ogletree, M., Biftu, T.  “SAR Of Heterocyclic Core Analogs Of A Direct Thrombin Inhibitor.”  244th ACS National Meeting, Philadelphia,  August 2012, abstract # MEDI 386 (poster).

Blizzard, T.A., Chen, H., Kim, S., Wu, J., Gude, C., Imbriglio, J., Bodner, R., Young, K., Park, Y.W., Ogawa, A.M, Raghoobar, S.L, Painter, R.E., Hairston, N.N., Wisniewski, D., Lee, S.H., Misura, A.S., Galgoci, A., Powles, M.A., Ha, S., Fitzgerald, P., Sharma, N., Lu, J., Hermes, J.D., Hammond, M.L., Wu, J., Park, T.,  Felcetto, T., Fitzgerald, P.M.D., Sharma, N., Ha, S. “Discovery of MK-7655: A Beta-Lactamase Inhibitor For Combination With Primaxin®.” 42nd National Organic Symposium, Princeton NJ, June 2011 (poster).

Blizzard, T.A.  “Discovery Of MK-7655: A beta-Lactamase Inhibitor For Combination With Imipenem.” Cambridge Healthech Institute Sixth Annual Drug Discovery Chemistry Symposium, San Diego, CA, April 2011 (invited lecture).

Blizzard, T.A.  “Overcoming Bacterial Resistance To Beta-Lactam Antibiotics.  A Tale Of Two Drug Discovery Programs.”  University Of Mississippi, Oxford MS, October 2010 (invited lecture).

Blizzard, T.A., Chen, H., Kim, S., Young, K., Ogawa, A.M, Raghoobar, S.L, Painter, R.E., Hairston, N.N., Lee, S.H., Misura, A.S., Hickey, E., Hermes, J.D., Hammond, M.L., Wu, J., Park, T.,  Felcetto, T., Fitzgerald, P.M.D., Sharma, N., Ha, S. “SAR Of Bridged Monobactam Beta-Lactamase Inhibitors (BLIs): Discovery Of A Class C BLI For Combination With Imipenem.” Advanced Pharmaceutical Chemistry Conference, Boston, MA, May 2009 (poster).

Blizzard, T.A., DiNinno, F., Morgan, J.D., Chen, H.Y., Wu, J.Y., Kim, S., Chan, W., Birzin, E.T., Yang, Y.T., Pai, L., Hayes, E.C., DaSilva, C.A., Mosley, R.T., Fitzgerald, P.M.D., Sharma, N.D., Rohrer, S.P., Schaeffer, J.M., and Hammond, M.L.  “ Dihydrobenzoxathiin SERAMs: Discovery of an Optimized Antagonist Side Chain and Application of Novel Side Chains to Existing Platforms.” 230th ACS National Meeting, Washington, D.C., August 2005, abstract # MEDI 29 (poster).

Blizzard, T.A., DiNinno, F., Morgan, J.D., Wu, J.Y., Chen, H.Y., Kim, S., Chan, W., Birzin, E.T., Yang, Y.T., Pai, L., Zhang, Z., Hayes, E.C., DaSilva, C.A., Tang, W., Rohrer, S.P., Schaeffer, J.M., and Hammond, M.L.  “Side Chain SAR Of Dihydrobenzoxathiin SERAMs: Bicyclic And Heteroatom Substituted Side Chains.”  228th ACS National Meeting, Philadelphia, August 2004, abstract # MEDI 294 (poster).

Blizzard, T.A., Mosley, R.T., Birzin, E.T., Chan, W.T., and Hammond, M.L.  “Comparison of 2-Phenylspiroindenes and 2-Phenylspiroindenediones as Estrogen Receptor Ligands.”  226th ACS National Meeting, New York, September 2003, abstract # MEDI 223 (poster).

Blizzard, T.A., Morgan, J.D., Mosley, R.T., Birzin, E.T., Frisch, K., Rohrer, S.P., and Hammond, M.L. “2-Phenylspiroindenes and 2-Phenylspiroindenediones as Novel Estrogen Receptor Ligands (SERMs).”  36th ACS Middle Atlantic Regional Meeting, Princeton, June 2003, abstract # 74 (invited lecture).

Blizzard, T.A., Morgan, J.D., Mosley, R.T., Frisch, K., Birzin, E.T., Rohrer, S.P., and Hammond, M.L.  “2-Phenylspiroindenes: A Novel Class of Selective Estrogen Receptor Modulators (SERMs).”  224th ACS National Meeting, Boston, August 2002, abstract # MEDI 357 (poster).

Blizzard, T.A.  “Chemistry And Biology Of Semi-Synthetic Avermectins.”  Long Island ACS Section Meeting, Hofstra University, NY, March 1998 (invited lecture).

Blizzard, T.A.  “Unexpected Methylenation And Dimerization During Attempted Fluorination Of A Carbanion With N-Fluoro-N-Methyl-Toluenesulfonamide.”  214th ACS National Meeting, Las Vegas, September 1997, abstract # ORGN 253 (poster).

Blizzard, T.A.  “Unexpected Products In Organic Synthesis.”  Koji Nakanishi 70th birthday symposium, Columbia University, May 1995 (invited lecture)

Blizzard, T., Margiatto, G., Mrozik, H., and Fisher, M.  “A Novel Fragmentation Reaction of Avermectin Aglycones.”  205th ACS National Meeting, Denver,  April 1993, abstract # ORGN 300 (poster).

Blizzard, T., Margiatto, G., Mrozik, H., Shoop, W., Frankshun, R., and Fisher, M.  “Synthesis and Biological Activity of 13-epi-Avermectins:  Potent Anthelmintic Agents With An Increased Margin of Safety.”  203rd ACS National Meeting, San Francisco,  April 1992, abstract # MEDI 65 (poster).

Blizzard, T.A.  “Chemistry of Anti-parasitic Natural Products: Avermectins and Paraherquamide.”  University of Ottawa; Ottawa, Canada, September 1991 (invited lecture).

Blizzard, T.A., Mrozik, H., Preiser, F.A., and Fisher, M.H.  “Synthesis, Reactivity, and Bioactivity of Avermectin B1-3,4-oxide. “  199th ACS National Meeting, Boston, April 1990, abstract # ORGN 2 (poster).

Blizzard, T.A., Marino, G., Mrozik, H., Fisher, M.H., Hoogsteen, K., and Springer, J.P  “Chemical Modification of Paraherquamide. Unusual Reactions and Absolute Stereochemistry.”  197th ACS National Meeting, Dallas, April 1989, abstract # ORGN 26  (poster).

Blizzard, T.A., Mrozik, H., and Fisher, M.H. “Chemical Degradation of Avermectin B1.”  195th ACS National Meeting, Toronto, Canada; April 1988, abstract # ORGN 119  (poster).